Rybelsus

Rybelsus tablets (semaglutide) are prescribed for adults with type 2 diabetes mellitus to control blood sugar levels. They contain the same active ingredient as WeGovy Injection and are taken once daily alongside diet and exercise. Rybelsus works by increasing insulin release, decreasing glucagon secretion, and may slow gastric emptying after meals. It belongs to the class of GLP-1 receptor agonists.

Order within

  • 00h
  • 00m
  • 00s

to receive your order on Monday December 23, 2024

*Product images are for illustrative purposes only, and you may receive a different licensed alternative.
Price Checker

£175.00£345.00

related products

You may also like

More Product information

Frequently Asked Questions - FAQs

What is Rybelsus?

Rybelsus is an oral prescription medication which uses the active ingredient, Semaglutide, for the management blood sugar levels in type 2 diabetes. It is considered highly effective when used alongside lifestyle changes such as dietary restrictions and increased physical activity.

Rybelsus’s primary mechanism of action involves increasing insulin secretions, improving insulin sensitivity and decreasing glucose release from the Liver. It can also help in weight loss in type 2 diabetics by reducing appetite and creating a sense of fullness in the stomach which reduces cravings for sugar and excess food.

You can find the Rybelsus price, per dose easily at our Website . You can also order Rybelsus online from Meds For Less easily, conveniently and reliably for next day delivery to your home address.

It contains the active ingredient, Semaglutide, a mimetic of a hormone called Glucagon Like Peptide-1 (GLP-1). 

By mimicking GLP-1, Semaglutide can increase insulin secretion via the pancreas, increasing the body cell’s sensitivity to insulin and decreasing appetite. 

These effects help to lower blood sugars and assist in the control of diabetes. 

Rybelsus is recommended to be taken alongside lifestyle changes such as dietary restrictions and increased physical activity. It is not recommended for type 1 diabetics or those people who are prone to having episodes of diabetic ketoacidosis (DKA). 

How Rybelsus works?

Rybelsus uses the active ingredient Semaglutide to act on receptors of the hormone Glucagon Like Peptide -1 (GLP-1) and regulate insulin secretion, insulin sensitivity and reduce appetite. Through this mechanism, Rybelsus achieves the following functions:

  • Rybelsus prompts the pancreas to release insulin when blood sugar levels are high. This “glucose-dependent” mechanism is helpful as it allows the lowering of blood sugars only when they are elevated and prevents a state of low blood sugar (hypoglycaemia). 
  • Rybelsus also reduces the secretion of a hormone known as glucagon to prevent any further rises in blood sugar if levels are already high.
  • Rybelsus also slows the rate at which food leaves the stomach (gastric emptying) and hence reduces sugar absorption into the bloodstream and helps to provide sharp spikes in blood sugar levels after meals.
  • Rybelsus promotes satiety and reduces appetite by acting on hunger centers in the brain. Reduced appetite and reduced feeding leads to lower blood sugar levels and weight loss. 

These combined functions of Rybelsus help to lower blood sugar, increase the efficiency of the body’s insulin response and support weight loss, all of which are needed to manage type II diabetes effectively. 

Benefits of Rybelsus for Type 2 Diabetes

Rybelsus uses the active ingredient Semaglutide and as such, offers various benefits in the management of type 2 diabetes. Some of the key benefits for type 2 diabetes are:

  • Good blood sugar control, preventing health complications of diabetes
  • Being a convenient oral pill option to help with blood sugar control
  • Reducing appetite and supporting weight loss which improves insulin sensitivity
  • Increasing glucose-dependent insulin secretion which allows steady blood glucose levels 
  • Lowering the risk of major cardiovascular events such as a heart attack or stroke

Weight loss potential

Rybelsus uses the active ingredient Semaglutide and though the concentrations of Semaglutide in Rybelsus are effective for blood sugar control, its effects have also shown potential for weight loss.

 The methods by which Rybelsus supports weight loss include:

  • Acting on the appetite centres in the brain and reducing hunger and calore intake
  • Slowing gastric emptying which creates a feeling of fullness, thereby reducing the likelihood of overeating or frequent snacking
  • Stabilising blood sugar levels and preventing the spikes and drops which cause sugar cravings. 

Rybelsus has shown to help type 2 diabetes lose a moderate amount of weight when combined with lifestyle changes such as reduced calorie diet and increased physical activity. 

The effect Rybelsus may have for your own weight loss depends on individual factors such as your lifestyle and initial bodyweight. Please consult with your healthcare advisor about using Rybelsus for weight loss and how that can benefit your diabetes management. 

Side effects

Like most medications, Rybelsus has the risk of some side effects.

The more common but less severe side effects of Rybelsus include:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Dizziness
  • Fatigue 

The rarer but more severe side effects of Rybelsus include:

  • Pancreatitis – inflammation of the pancreas which can cause a combination of severe abdominal pain, nausea and vomiting
  • Kidney issues leading to dehydration
  • Hypoglycaemia (Low blood Sugar), leading to fainting – especially if using other hypoglycemic drugs such as Insulin or Sulfonylureas.
  • Allergic reactions such as swelling of the lips, tongue, throat or trouble breathing. 

If you experience any of these rare but more serious side effects of Rybelsus, please seek medical attention immediately. 

For a more exhaustive list of side effects, please consult the patient information leaflet in the medicines pack or speak to. Your healthcare provider. 

Precautions

When Using Rybelsus, its important to take some necessary precautions to ensure safe and effective use. These precautions include:

  • Proper use of Rybelsus (Please see a brief list of instructions below or consult the comprehensive list in the patient information leaflet)
  • Being alert for symptoms of Pancreatitis such as Severe stomach pain, nausea and vomiting
  • Not taking Rybelsus if you have a personal or family history of Medullary thyroid carcinoma or Multiple Endocrine Neoplasia Syndrome type 2 (MENs)
  • Rybelsus can cause nausea, vomiting and diarrhea, this can cause dehydration and damage the kidney. Ensure you stay well hydrated when taking Rybelsus to prevent kidney damage.
  • Rybelsus can increase the risk of hypoglycaemia (low blood sugars), particularly when taken with other hypoglycemic drugs like Insulin or Sulfonylureas.

o A good precaution to take is regular monitoring of blood glucose levels and being mindful about symptoms of hypoglycaemia.

o Please speak to your healthcare provider about the use of Rybelus when driving or operating heavy machinery due to the risk of hypoglycaemia. 

Important Considerations

Some important considerations when taking Rybelsus are:

  • The possibility of allergic reactions to Rybelsus, if you have any allergies to Rybelsus or other GLP-1 mimetics, please let your healthcare provider know to allow for safe prescribing practices.
  • Increased risk of pancreatitis
  • Increased risk of thyroid cancer particularly with a personal or family history of Medullary thyroid carcinoma or Multiple Endocrine Neoplasia Syndrome type 2 (MENs)
  • Decreased kidney function and an increased risk of dehydration, especially with the nausea and vomiting
  • The risk of hypoglycaemia ,especially with other blood sugar lowering medicines such as Insulin or Sulfonylureas (Such as Glipizide).
  • It is not advisable to take Rybelsus in a state of pregnancy due to the potential risk to the fetus. If you are pregnant or planning on becoming so, please speak to your healthcare provider about reducing or replacing the use of Rybelsus,
  • It is also not advisable to use Rybelsus when breastfeeding due to the risk of it passing to the baby through breast milk. 

Rybelsus tablets are used for the management of type 2 diabetes, its main purpose is to help lower and stabilise blood sugar levels as part of a comprehensive treatment plan which involves lifestyle changes and other medications.

Rybelsus improves blood sugar control by improving insulin secretion, enhancing the body’s sensitivity to insulin and reducing glucose release from the liver.

Rybelsus can also be used for weight loss in type 2 diabetics by reducing appetite, creating a sense of fullness in the stomach and reducing calorie intake. Rybelsus weight loss, reduced calorie intake and good glucose control makes this an  effective medication for managing diabetes.

Rybelsus should be taken using the following general instructions:

  • Take Rybelsus once daily, first thing in the morning on an empty stomach at least 30 minutes before eating or drinking anything apart from water.
  • Swallow the tablet whole without crushing, chewing or breaking it
  • If you miss a tablet, take it as soon as you remember within 5 days. If it has been more than 5 days  since the missed dose, please skip it and continue as normal. Do not take 2 doses at once to compensate for a skipped dose.

Your healthcare provider may start you on an initial low dose of Rybelsus  (3mg) and gradually increase it to a maintenance dose of 14mg . This will help your body tolerate the effect of the medication and help you effectively manage any side effects. 

Rybelsus is a prescription-only medication that cannot be purchased Over the Counter (OTC). It can only be prescribed by a suitable healthcare provider for the management of blood sugar levels in type 2 diabetes.

Regular follow ups will be needed with your healthcare provider to monitor the effectiveness of Rybelsus and the management of any potential side effects. 

For the full list of Rybelsus cost per dose and per number of tablets, please look online at Meds For Less.

Rybelsus can be taken with other medications however this should be done under the care of a healthcare provider to watch for and avoid unfavorable drug interactions. 

Rybelsus is often taken alongside other diabetes medications such as Metformin however certain diabetes medicines combinations require caution due to the risk of low blood glucose levels (hypoglycaemia). These medicines include Insulin or Sulfonylureas, such as Glipizide and glimepiride. 

Rybelsus can be safely taken alongside medicines used in the treatment of blood pressure or blood cholesterol such as ACE inhibitors, statins or diuretics. However it is advisable to inform your healthcare provider about the medications you are taking. 

Due to Rybelsus’s effects on slowing gastric emptying, medications meant for the treatment of gastrointestinal problems, pain relievers or anti-nausea drugs may need to have their doses adjusted to provide effective treatment. 

Rybelsus can increase the risk of thyroid tumours, while there is no risk of adverse interactions with thyroid medicines, it may be beneficial to consult your healthcare provider about any thyroid conditions you may have. 

Rybelsus is effective for weight loss as it uses the active ingredient, Semaglutide.

Although the concentration of Semaglutide in Rybelsus is more appropriate for the treatment and management of blood sugar levels in type 2 diabetics, its GLP-1 mimetic functions can also help with weight loss.

Rybelsus can help with weight loss by inhibiting appetite, creating a sense of fullness in the stomach and reducing cravings for sugar (food).

When used with lifestyle changes, Rybelsus has been shown to help people lose 5-10% of body weight within 6 months to a year.

This is variable however,  due to individual factors such as lifestyle, individual response and starting weight of those taking the medicine. 

Recently Viewed