Amitriptyline (Accord Brand)

Amitriptyline is a tricyclic antidepressant used to treat various conditions in adults. Some of these include, major depressive episodes, neuropathic pain, chronic tension-type headache prophylaxis, and migraine prophylaxis.
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Frequently Asked Questions - FAQs

Amitriptyline (Accord Brand)
Amitriptyline belongs to a class of medications known as tricyclic antidepressants. It is believed to function by increasing the level of serotonin in the brain, which can enhance mood. Additionally, it alters how nerves perceive pain signals, effectively reducing pain. This makes amitriptyline useful for treating symptoms related to pain relief or migraines.
 
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Some medicines may affect the action of other medicines and cause serious side effects. Inform your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, such as monoamine oxidase inhibitors (MAOIs) like phenelzine, iproniazid, isocarboxazid, nialamide, or tranylcypromine (used to treat depression), or selegiline (used to treat Parkinson’s disease), which should not be taken with Amitriptyline tablets. Other medicines to be cautious of include adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine, and phenylpropanolamine (found in some cough or cold medicines and anaesthetics); high blood pressure medications like calcium-channel blockers (e.g., diltiazem, verapamil), guanethidine, betanidine, clonidine, reserpine, and methyldopa; anticholinergic drugs for Parkinson’s disease and gastrointestinal disorders (e.g., atropine, hyoscyamine); thioridazine (for schizophrenia); painkillers like nefopam, tramadol, and morphine; buprenorphine (for severe pain or opioid addiction), which may cause symptoms like muscle contractions, agitation, hallucinations, coma, excessive sweating, tremors, increased reflexes, muscle tension, and high body temperature; antifungal medications (e.g., fluconazole, terbinafine, ketoconazole, itraconazole); sedatives (e.g., barbiturates); antidepressants (e.g., SSRIs like fluoxetine, paroxetine, fluvoxamine, duloxetine, bupropion); certain heart medications (e.g., beta blockers, antiarrhythmics); cimetidine (for stomach ulcers); and methylphenidate (for ADHD). Contact your doctor if you experience any adverse symptoms. For a full list refer to the Patient Information Leaflet.
 
For alternatives to Accord brand Amitriptyline,  you can visit our Anxiety And Depression
Side effects of Amitriptyline have been reported with varying frequencies. Very common side effects (affecting more than 1 in 10 people) include sleepiness or drowsiness, shakiness of hands or other body parts, dizziness, headaches, dizziness when standing up due to low blood pressure (orthostatic hypotension), irregular, hard, or rapid heartbeat, dry mouth, constipation, nausea, excessive sweating, weight gain, slurred or slow speech, aggression, and a congested nose. Common side effects (affecting up to 1 in 10 people) include confusion, sexual disturbances (decreased sex drive, problems with erection), disturbance in attention, changes in taste, numbness or tingling in the arms or legs, disturbed coordination, dilated pupils, heart block, fatigue, low sodium concentration in the blood, agitation, urination disorders, and feeling thirsty. Uncommon side effects (affecting up to 1 in 100 people) include excitement, anxiety, difficulties sleeping, and nightmares. For a full list refer to the Patient Information Leaflet.

The active substance in the tablets is amitriptyline hydrochloride, with each tablet containing either 10 mg, 25 mg, or 50 mg of the active ingredient. The other ingredients include lactose monohydrate, microcrystalline cellulose (E460), maize starch, colloidal anhydrous silica, magnesium stearate, hypromellose (E464), titanium dioxide (E171), and macrogol. Additionally, the 10 mg tablet contains indigo carmine (E132). The 25 mg tablet includes talc (E553b), quinoline yellow (E104), iron oxide (E172), sunset yellow (E110), and indigo carmine (E132). The 50 mg tablet contains talc (E553b), quinoline yellow (E104), and iron oxide (E172). For further details refer to the  Amitriptyline PIL.

Amitriptyline is available for purchase online at Meds for Less. All you need to do is complete a brief consultation process to get started. For alternatives to Accord brand Amitriptyline,  you can visit our Anxiety And Depression Treatment page where you can buy amitriptyline and browse our comprehensive range of treatment options and see alternatives such as Amitriptyline.         

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