Wegovy

Wegovy (semaglutide) is one of the many Weight Loss Products we sell at Medsforless. It is an injectable medication designed for weight loss in individuals with a BMI exceeding 30. It’s also prescribed for those with a BMI over 27 who have accompanying weight-related health issues such as high blood pressure, diabetes, heart disease, and elevated cholesterol levels. By mimicking a natural hormone in the gut, Wegovy aids in appetite control and induces a sensation of fullness.

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to receive your order on Friday January 24, 2025

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£159.99£796.99

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What is Wegovy?

Wegovy is a prescription weight loss medication that is primarily in the treatment of obesity.

It contains the active ingredient Semaglutide which helps to reduce appetite, maintain a feeling of fullness in the stomach and reduce cravings. 

Wegovy is taken as an injectable medicine once a week and is quick and easy to use. 

Buying Wegovy online is now easier than before, you can safely, reliably and easily from Meds for Less and expect delivery to your home address within 24 hours.

Wegovy is a prescription, injectable medication that is used primarily for the treatment of obesity and weight management. It contains the active ingredient Semaglutide, a synthetic product which mimics the natural hormone, Glucagon-like peptide-1 (GLP-1).

In the context of obesity, GLP-1 helps regulate appetite and reduce food intake by acting on appetite centres in the brain. This helps people feel fuller sooner, reduces cravings, helps people eat less and allows for weight loss.

Some diabetes control medications also use the active ingredient Semaglutide for their purposes, however the dose of Semaglutide is higher in Weight loss medications like Wegovy than in diabetes medications, like Ozempic. 

Wegovy Price

Please find the Injectable Wegovy Cost of purchase in the table below according to the dosage and number of injections available. 

Wegovy Dose 1-month supply 2-month supply 3-month supply
0.25 mg £159.99 £318.99 £477.99
0.5 mg £159.99 £318.99 £477.99
1 mg £159.99 £318.99 £477.99
1.7 mg £223.99 £445.99 £668.99
2.4 mg £267.99 £529.99 £796.99

Wegovy vs Saxenda

Wegovy and Saxenda are both injectable weight loss medications, however they differ in their active ingredients, dosing, effectiveness and administration schedules.

 Wegovy contains the active ingredient Semaglutide which helps to reduce appetite, promote a feeling of fullness and reduce food intake. Saxenda uses the active ingredient, Liraglutide which also promotes a feeling of fullness and reduces cravings for food, however it has a shorter duration of action compared to Semaglutide.

 Due to having a longer dose of action, the maintenance dose of Wegovy only needs to be administered once a week however the shorter acting Liraglutide needs to have its maintenance dose taken once a day.

Wegovy has shown to have a 15-20% effectiveness in weight loss in a year when combined with diet and exercise. Saxenda’s effectiveness averages around 5-10% loss of initial body weight over a year.

 Saxenda and Wegovy are approved for use in individuals who have a BMI of 30 kg/m2  (classified obese) or BMI of 27 kg/m2 with a weight related condition (like hypertension or type II diabetes).

In countries including the UK, Saxenda has been approved for the use of adults and adolescents (from 12 and above) with obesity whereas Wegovy is only approved for the use of adults (18 and above).

 Both, Saxenda and Wegovy have similar side effect profiles since both medicines have active ingredients which act as GLP-1 mimetics. These side effects tend to include nausea, vomiting, constipation, headache and gut discomfort. The side effects are usually more prominent at the start of treatment or during dose increases.

How to Take Wegovy

Wegovy is a prescription injectable medication with an initial dose of 0.25 mg once weekly for the first month. Dose increases occur once every 4 weeks until a maintenance dose of 2.4mg once weekly is reached. A sample dosing timetable is given below:

 Weeks 0-4: 0.25mg once weekly

Week 5-8: 0.5 once weekly

Week 9-12: 1mg once weekly

Week 13-16: 1.7mg once weekly

Week 17 onwards: maintenance dose of 2.4mg once weekly

 The low initial dose and subsequent gradual increase helps patients tolerate the effects and side effects of the medication. Please speak to your healthcare provider about the appropriate dosing and administration schedule for the  Injectable Wegovy pen.

 Wegovy comes as injectable pen with a certain fixed supply of doses. The pen can be

injected under the skin (subcutaneously) in areas like the abdomen, thigh and upper arm. Wegovy should be taken on the same day each week but it can be taken anytime of the week, with or without food. 

Can Wegovy Help with Other Conditions?

WeGovy can help with other conditions, particularly those related to obesity as the effects of weight management can improve metabolic health and reduce the risk factors for other diseases. 

Wegovy’s active ingredient Semaglutide can be used in diabetes treatment as demonstrated by diabetes medications Ozempic and Rybelsus . Semaglutide, in its function as a GLP-1 mimetic, increases insulin sensitivity of the body’s cells and insulin secretion by the pancreas. 

This is in addition to the helpful weight loss effects it exerts by decreasing appetite leads to a combination effect that can help regulate and reduce blood sugars and help treat diabetes.

 Wegovy can help treat Non-alcoholic Fatty Liver Disease (NAFLD), a condition normally associated with obesity and insulin resistance. Wegovy’s ability to increase insulin sensitivity and cause weight loss can be very helpful in treating NAFLD.

 Obesity is a major risk factor for heart disease, and high blood pressure, Wegovy’s weight loss effects can help lower blood pressure, lower cholesterol levels and overall cardiovascular strain.

 Wegovy’s weight loss effects can also help reduce the severity and effects of conditions like Obstructive Sleep Apnoea, Joint pain and Osteoarthritis, as well as Polycystic Ovary Syndrome. 

Is Wegovy Effective for Weight Loss?

Wegovy contains the active ingredient Semaglutide at a dose that is meant for weight loss. It has been proven in clinical trials to help people loose 15-20% of their body weight within 68 weeks (1 + year) when combined with a reduced calorie diet and increase physical activity.

 Lifestyle changes alone were shown to only have a 5-10% effect on weight loss. Semaglutide’s effect on reducing appetite and increasing satiety can also make it easier to stick to a reduced calorie diet by helping increase the feeling of fullness in the body. 

Contraindications & Drug Interactions

Wegovy has some contraindications (situations it shouldn’t be used in) and potential drug interactions. 

Contraindications for Wegovy include:

  • Having a personal or family history of thyroid medullary cancer as Wegovy can increase the chances of developing this condition.
  • Having a genetic condition known as Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2)
  • Being allergic to Semaglutide (the active ingredient in Wegovy)
  • Being pregnant or breastfeeding
  • People with a history of diabetic retinopathy should use caution when using Wegovy 

Medications to use with caution due to the potential of drug interaction include:

  • Insulin and other hypoglycaemic medications like Sulfonylureas due to the risk of dangerously low blood sugars
  • Medications with a very narrow therapeutic index (narrow safe dose), due to Wegovy slowing gastric emptying and hence increasing the risk of accidental overdose
  • Drugs such as corticosteroids or antipsychotics which can raise blood sugar levels as these can interact with Wegovy and decrease its effectiveness
  • Other GLP-1 mimetics (such as Ozempic or Rybelsus) due to the risk of increasing side effects without additional benefits. 

Wegovy and Pregnancy

Wegovy is not recommended to be taken during pregnancy due to the potential risks to the developing fetus.  Although very few human studies have been performed on the effects of Semaglutide (Wegovy’s active ingredient) in pregnancy, animal studies have shown that Semaglutide to be harmful to the developing fetus.

Women who are on Wegovy and are thinking of trying to conceive are advised to discontinue Wegovy atleast 2 months before trying to conceive.

Aside from Semaglutide/Wegovy’s potential harmful effects on the womb,  intentional weight loss (even through other methods) are not recommended during pregnancy due to the independent effect of weight loss on the developing fetus. 

Side Effects

Like most medications, Wegovy has a range of side effects that can vary in intensity and type. The more common side effects are typically less serious however the less common side effects tend to be a bit more severe.

Common side effects include:

  •       Nausea
  •       Vomitting
  •       Diarrohea
  •       Constipation
  •       Abdominal pain/discomfort
  •       Decreased appetite
  •       Fatigue
  •       Headaches

Rarer but more serious side effects include:

  •       Thyroid tumours
  •       Kidney problems causing severe diarrohea or vomiting in the short-term and kidney damage in the long term
  •       Diabetic retinopathy
  •       Allergic reactions such as a rash, itching; swelling of the face, lips, tongue or throat and difficulty breathing.

If you experience any of the rarer yet more serious side effects of Wegovy, please seek medical attention immediately. 

Wegovy Alternatives

There are some alternatives to Wegovy that can be used for weight loss by affecting appetite and metabolic pathways, these options include:

  •       Ozempic
  1. Ozempic is another injectable medication that uses Semaglutide as an active ingredient, however the concentrations of semaglutide are lower in Ozempic than in Wegovy.
  2. Ozempic is primarily used in the treatment of diabetes due to Semaglutide’s ability to regulate insulin secretion and sensitivity, however it can be prescribed off-label by healthcare providers to manage weight loss.
  •       Saxenda
  1. Saxenda is also an injectable medication which uses the active ingredient, Liraglutide. Liraglutide is also a GLP-1 mimetic like Semaglutide, however as opposed to weekly injections, it requires daily injections. The weight loss achieved by Saxenda is 5-10% as opposed to the 15-20% achieved by Wegovy. 
  •       Mounjaro
  1. Mounjaro is a new injectable medication which uses the active ingredient Tirzepatide. Tirzapetide targets both the GLP-1 receptors and Glucose-Dependent Insulinotropic Polypeptide (GLP) receptors which enhances appetite regulation, blood sugar management and weight loss. 
  •       Orlistat
  1. Orlistat is the active ingredient in oral medications like Alli (Over the Counter) and Xenical (Prescription). It can help in weight loss by blocking fat absorption in the intestines.

 For finding out about other alternatives to Wegovy, or other methods of weight loss or diabetes control, please speak to your healthcare provider.

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